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Prediction of uridine modifications in tRNA sequences

from BMC Bioinformatics – Latest Articles http://ift.tt/1xEwjXw


The T box riboswitch: A novel regulatory RNA that utilizes tRNA as its ligand.

The T box riboswitch: A novel regulatory RNA that utilizes tRNA as its ligand.

Biochim Biophys Acta. 2014 May 7;

Authors: Henkin TM

The T box riboswitch is a cis-acting regulatory RNA that controls expression of amino acid-related genes in response to the aminoacylation state of a specific tRNA. Multiple genes in the same organism can utilize this mechanism, with each gene responding independently to its cognate tRNA. The uncharged tRNA interacts directly with the regulatory RNA element, and this interaction promotes readthrough of an intrinsic transcriptional termination site upstream of the regulated coding sequence. A second class of T box elements uses a similar tRNA-dependent response to regulate translation initiation. This review will describe the current state of our knowledge about this regulatory system. This article is part of a Special Issue entitled: Riboswitches.

PMID: 24816551 [PubMed – as supplied by publisher]

from pubmed: rna ligand interacti… http://ift.tt/1oUyyyN

RNA Symposium: “RNAs never stop”

via anbiophy.snv.jussieu.fr


Chemical & Engineering News: Protein Factory Reveals Its Secrets


Décoder le vivant: les dessous du ribosome


Ribosome Translation


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