RNomics

Home » Posts tagged 'primates'

Tag Archives: primates

Comparative and demographic analysis of orang-utan genomes

Media_httpwwwnatureco_cdfyl

We estimated nucleotide divergence in unique gap-free sequence, indicated at each node, from the alignment of rhesus macaque (yellow), gibbon (purple), orang-utan (orange), gorilla (aqua), chimpanzee (green) and human (blue) whole genome shotgun reads to the human reference (Hs.35; Supplementary Information section 3). Note that the Bornean (P. pygmaeus) and Sumatran (P. abelii) orang-utan species showed nucleotide identity comparable to that of bonobo (Pan paniscus) and chimpanzee (Pan troglodytes). Estimates of divergence time based on sequence identity are indicated at each node, ~1Myr implies approximately 1Myr or less. Values taken from refs 29 and 30 where indicated.

 


Media_httpwwwnatureco_sfovy

We identified six genes (indicated in yellow) under moderate to strong positive selection in primates (P<0.05) that fall within the cerebroside-sulphatid region of the sphingolipid metabolism pathway (adapted from human KEGG pathway 00600). This pathway is associated with several human lysosomal storage disorders, such as Gaucher’s disease, Sandhoff’s disease, Tay-Sachs disease and metachromatic leukodystrophy. Abbreviations, annotations and connections are presented in accordance with KEGG standards: solid lines represent direct relationships between enzymes (boxes) and metabolites (circular nodes), dashed lines represent indirect relationships, arrowheads denote directionality (see http://www.genome.jp/kegg-bin/show_pathway?map00600 for further details).


Advertisements

Le chaînon Ida

 

 

 

universcience.tv

Réalisation : Arno Caravel

Production : universcience.tv

Date de production : 2010

de Colin Tudge,
Éd. J.-C. Lattès, 2009.
Véritable enquête sur la découverte et l’étude d’Ida, fossile de 47 millions d’années, à l’origine de percées spectaculaires dans la recherche sur les ancêtres des primates.

Pour découvrir tous les livres de cette série aller dans MENU (sous la vidéo).

http://www.universcience-vod.fr/media/880/le-chainon-ida.html?spage=1&sea…

 

Climate Change and Human Evolution Video | Smithsonian Human Origins Program

The Neandertal Genome – Background

Media_httpwwwsciencem_mvdzz

The Neandertal Genome Because Neandertals are much closer kin to us than are chimpanzees, which diverged from the human lineage 5 to 7 million years ago, matching Neandertal DNA against our own has the potential to reveal genetic changes that help define who we are. http://www.sciencemag.org/special/neandertal/feature/index.html

Xqy3m

Neanderthal genes ‘survive in us’

http://news.bbc.co.uk/2/hi/science/nature/8660940.stm

 

 

Exploratorium | Evidence | How Do We Know What We Know? | Human Origins

Sfn2q

http://www.exploratorium.edu/evidence/

%d bloggers like this: