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Viroids: Survivors from the RNA World?

Originally posted on MicrobiologyBytes:

Viroid A new review in Annual Review of Microbiology gives an excellent introduction to viroids.

Contents:

  • Introduction: Why The Need For An RNA World?
  • Viroids: Essential Features
  • Discovery of a Subviral World
  • Structure: Small Circular RNAs with Compact Folding
  • Replication: Rolling-Circle Mechanism Catalyzed by Enzymes and Ribozymes
  • Sequence Diversity
  • Viroid-Related Replicons
  • Viroid-Like Satellite RNAs
  • Retroviroid-Like Elements
  • Hepatitis δ virus
  • Why Are Viroids And Viroid-Related Replicons Regarded As Survivors Of The RNA World?
  • Early Speculations on the Origin of Viroids
  • Circular RNAs: Relics of Precellular Evolution?
  • Viroid-Related Replicons
  • Summary

Viroids: Survivors from the RNA World? (2014) Annual Review of Microbiology, 68(1): 395-414. doi: 10.1146/annurev-micro-091313-103416

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Origin of Life | The Advanced Apes | PBS Digital Studios

Origin of Life | The Advanced Apes | PBS Digital Studios.

Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome

 

Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome.

Interactions of the EF4-CTD in the PTC.

Interactions of the EF4-CTD in the PTC.

 

 

 

Modified CRISPR Expands Targets | The Scientist Magazine®

Modified CRISPR Expands Targets | The Scientist Magazine®.

Modified CRISPR Expands Targets | The Scientist Magazine®

CSHLKnowing what to keep and what to trash: how an enzyme distinguishes cellular messages

CSHLKnowing what to keep and what to trash: how an enzyme distinguishes cellular messages | Article-Joshua-Tor | News & Features.

CSHLKnowing what to keep and what to trash: how an enzyme distinguishes cellular messages | Article-Joshua-Tor | News & Features

A Synthetic Biology Approach Identifies the Mammalian UPR RNA Ligase RtcB: Molecular Cell

A Synthetic Biology Approach Identifies the Mammalian UPR RNA Ligase RtcB: Molecular Cell.

Mammalian UPR RNA Ligase RtcB

The RNA Enigma

 

The RNA Enigma.

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine | eLife

 

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine | eLife.

The Origins and Evolution of the Ribosome

via The Origins and Evolution of the Ribosome.

Genomic differences between individuals can change the physical organization of RNA transcripts

The information contained within a messenger RNA (mRNA) transcript goes beyond the protein recipe embedded in its sequence. mRNAs consist of single strands of nucleotides that can pair with each other in the same way as double-stranded DNA molecules. The resulting ‘secondary structures’ help determine when and how the encoded protein gets produced.

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